Dr. Ron Levy - Using Electrodes to Scramble Pain
Dr. Ron Levy discusses how electricity can be used to cure imbalances in certain parts of the brain circuits to have less pain symptoms.Read more
DESI Mass Spectrometry
Dr. Martin Kaufmann and Dr. David Berman discuss DESI (Desorption Electro-Spray Ionization), a mass spectrometry technique that images tissue based on their molecular mass.Read more
Dr. DJ Cook - The Beginning of the Future for Neurosurgery
Dr. DJ Cook discusses new surgical approaches that can be offered to patients with brain conditions, such as brain tumours and epilepsy.Read more
Using the NaviKnife in Surgery
Dr. Gabor Fichtinger, Dr. Tamas Ungi, and Dr. Caitlin T. Yeo discuss how the NaviKnife can take the guesswork out of surgery.Read more
Dr. DJ Cook - Brain Aneurysm Repair
Dr. DJ Cook performed a brain aneurysm repair. This is a surgical procedure used to treat a bulging blood vessel in the brain that’s at risk of rupturing or tearing open.Read more
Dr. Jay Engel - The iKnife
Dr. Jay Engel explains what the iKnife is, and how it is used in tumour removal surgical procedures.Read more
Dr S Nanji - Liver cancer and population-based studies
Department of Surgery, Queen's University https://surgery.queensu.ca/Read more
Dr. Nader Ghasemlou
Dr. Nader Ghasemlou and students in his lab are working to understand how the nervous and immune systems interact with each other to modulate pain outcomes. What they’ve discovered is that chronobiology or circadian rhythms - 24 hour rhythms, seasonal rhythms and lunar rhythms - have a huge effect on pain.Read more
Dr. Ian Gilron: Clinical Pain Research with patient Karen Kemp and research nurse Sylvia Robb
Estimates from studies suggest that between 20 and 30 percent of the global population suffer from chronic pain. It can have a significant physical, emotional, psychological, social and financial impact on an individual. Dr. Ian Gilron at The Pain Research Clinic is working to understand how new therapies can relieve symptoms and perhaps someday transform chronic pain into a rare condition.Read more
Queen's Cancer Research Institute
Queen's Cancer Research Institute is Canada’s only integrated cancer research centre where bench researchers (Cancer Biology and Genetics), clinical trials experts (Canadian Cancer Trials Group), and population/health services researchers (Cancer Care and Epidemiology), work together under one roof. We advance cancer research, care and prevention across Canada and around the world.
Learn more:
https://qcri.queensu.ca...Read more
Dr. Amber Simpson
Precision medicine uses data to better understand a person's cancer and how to treat it. Dr. Amber Simpson is a computer scientist working to mine imaging data to inform how to better treat patients.Read more
Dr. Diane Lougheed Cystic Fibrosis
About 1 in 30 North American Caucasians are carriers of the Cystic Fibrosis gene. Dr. Diane Lougheed talks about research into targeted gene therapy and how it's contributing to an increased survival rate - so much so that 60% of Canadians living with Cystic Fibrosis are adults.Read more
Dr. Diane Lougheed
Asthma is one of the most chronic respiratory conditions and affects approximately 8 - 12% of Canadians. Dr. Diane Lougheed of KGH Research Institute and Queen's University, and patient Tammy Ewart talk about the impact of asthma and how research is making a difference for those who suffer from this disease.Read more
Dr. Paula James Let's Talk Period
1 in 1000 people have a bleeding disorder - but most don't know it. A new website - letstalkperiod.ca - has a self-test to help people identify abnormal bleeding so that they can seek treatment.Read more
Dr. Paula James Hemophilia
Hemophilia is the most common severe bleeding disorder, having a significant impact on the lives of both those who have the disorder and 'carriers' of the disorder. New research into gene therapy, however, may mean that a cure could be possible in the near future.Read more
WJ Henderson Centre for Patient Oriented Research
Opened in September 2017, the W. J. Henderson Centre for Patient-Oriented Research provides outstanding opportunities for collaborative R&D into innovative materials, tools and treatments, leading to best practices and improved care.
This 10,000-square-foot interdisciplinary hub consolidates both inpatient and outpatient research into a single, in-hospital location. Shared access by researchers from multiple disciplines enables efficient and safe assessment, investigation and monitoring of people involved in...Read more
GIDRU
The Gastrointestinal Diseases Research Unit (GIDRU) houses a multidisciplinary team of clinician-scientists from the departments of Medicine, Surgery and Pathology, and Biomedical and Molecular Sciences. GIDRU is design to offer collaborative research and training opportunities to facilitate bench to bedside discovery. The facility includes state of the art laboratory space, as well as office and meeting areas to facilitate collaborative discovery....Read more
Dr. David Reed
Dr. David Reed is a Clinician Scientist at KGH Research Institute and Assistant Professor in the Division of Gastroenterology in the Department of Medicine at Queen's University. As a member of the Gastrointestinal Diseases Research Unit (GIDRU), Dr. Reed focuses on luminal signaling to nerves in the gastrointestinal tract and the role of this pathway in disorders such as irritable bowel syndrome. Read more
Dr. Stephen Vanner
Dr. Stephen Vanner is Director of the Gastrointestinal Diseases Research Unit (GIDRU) at Queen’s University, and a Clinician Scientist at KGH Research Institute. He also leads the Canadian Neurogastroenterology Network (CNN), a consortium of IBS researchers throughout Canada. His translational research program examines the pain mechanisms in irritable bowel syndrome and inflammatory bowel disease, with a goal of identifying new targets for the development of...Read more
Dr. Anne Ellis
Up to 40 percent of Canadians will be affected by an allergic condition at some point in their lives. Allergies can have a significant impact on daily life, including lost days at work or school and the financial burden of having to buy medications to relieve symptoms. Dr. Anne Ellis and her colleagues are studying the effectiveness of several types of anti-allergic treatments, using the...Read more
Walking Tour of WJ Henderson Centre
Take a look around the WJ Henderson Centre for Patient-Oriented Research. Read more
Dr. Jagdeep Walia
Dr. Walia’s clinical research focuses on gene therapy for neurodegenerative diseases, specifically GM2 gangliosidosis group comprising Tay Sachs, Sandhoff and GM2A deficiency. A second research interest involves study of genetics, epigenetics, metagenomics, and metabolomics of autism. He collaborates on many studies for inherited metabolic disorders in children and adults. His early research into these incurable neurodegenerative conditions has shown promising results, and he is in ...Read more
ARCH network
ARCH is an interdisciplinary, collaborative platform for sharing and profiling global health research that leads to positive change.
The Network:
• conducts research that provides evidence to inform and advance responses to inequity
• develops capacity to support ethical and impactful research practice
• translates knowledge to ensure research leads to action for positive change. Read more
A game-changing approach to heart surgery
The heart isn't just a pump, it's a sophisticated electric motor, and when its electronic signals misfire, it can disrupt the heart's regular rhythm. Cardiac arrhythmia causes symptoms such as fatigue, shortness of breath, dizziness, palpitations and even chest pain. For some patients, cardiac arrhythmia can be a debilitating, hard to treat, and even fatal disease. Read more
The Human Mobility Research Centre
The Human Mobility Research Centre is a collaborative hub for researchers and clinician-scientists working in medicine, engineering, health sciences and computer science. Read more
Training next-generation innovators
KGHRI clinician-scientists describe how student researchers from Queen's University and its teaching hospitals explore interdisciplinary opportunities, gain global experience and learn from leading researchers. Read more
KGHRI Annual Report 2016
Discovery today, treatment tomorrow. The Kingston General Hospital Research Institute (KGHRI) is the not-for-profit academic health research institute of Kingston General Hospital. We work in close collaboration with the Faculty of Health Sciences at Queen’s University and with our partner hospitals, Hotel Dieu Hospital and Providence Care, advancing research leading to better treatment and care of Canadians. Read more
Dr. Sue Bartels
How does war affect the health of women and children? Dr. Bartels is actively involved in global health research, primarily in conflict and disaster affected areas of the world. She recently used a unique storytelling method to study child marriage in Lebanon. Read more
Dr. Karen Yeates
Dr. Yeates’s research focuses on improving access to care for underserviced populations in Canada and sub-Saharan Africa. She was recently awarded the Rising Stars in Global Health award from Grand Challenges Canada for an initiative that uses smartphones to screen for cervical cancer. Read more
Dr. David Maslove
Dr. Maslove's research focuses on informatics, genomics, and the use of biomedical big data to address current challenges in Critical Care Medicine. Read more
Dr. Laura Wells
Age–related macular degeneration is a leading cause of vision loss, and currently requires aggressive treatments that include regular, multiple injections, resulting in a huge impact on a patient’s quality of life. Dr. Laura Wells, a KGH RI researcher working with the Human Mobility Research Centre, is working to create materials that can be used to deliver drugs for hard to reach areas of the eye, ...Read more
Dr. David Maslove
Should two patients with the same illness receive the same treatment?
Dr. David Maslove is a Clinician-Scientist who’s studying how to bring precision medicine to the Intensive Care Unit and how to tailor specific treatments to individual patients. By analyzing the large amounts of monitoring data collected within the ICU, Dr. Maslove can detect distinct differences in genetic or physiological traits and identify how patients...Read more
Dr. Neil Renwick
KGH RI clinician-scientist Dr. Neil Renwick uses an interesting analogy to describe his work in post-transcriptional gene regulation: one that involves cities, buses and maniacal taxi drivers.
“There are two major molecule groups that actually control genes – RNA binding proteins and microRNAs,” he says. “A cell is very much like a city and the RNAs are like people. RNA binding proteins are like buses ...Read more
Dr. Mark Ormiston
Pulmonary Arterial Hypertension (PAH) is a fatal disease that primarily affects women between the ages of 30 and 40. Dr. Mark Ormiston, a Canada Research Chair in cardiovascular regenerative medicine, is working to understand more about the interactions between the immune system and PAH to look for new therapies for this deadly disease.
“Natural killer cells are a component of the innate immune system,” says ...Read more
KGHRI Annual Report 2015
Discovery today, treatment tomorrow. The Kingston General Hospital Research Institute (KGHRI) is the not-for-profit academic health research institute of Kingston General Hospital. We work in close collaboration with the Faculty of Health Sciences at Queen’s University and with our partner hospitals, Hotel Dieu Hospital and Providence Care, advancing research leading to better treatment and care of Canadians. Read more
Dr. D.J. Cook with patient Sharon Dowdall
Brain aneurysms can lead to a stroke, with
devastating side effects that radically alter
a patient’s quality of life. Dr. D.J. Cook, a
cerebrovascular surgeon-scientist, is developing
new treatments that minimize trauma related
to brain aneurysm surgery, resulting in better
outcomes, shorter hospital stays and an earlier
return to normal life. He also runs a parallel
research ...Read more
Dr. Denis O'Donnell with patient Annetta Black
At first, Annetta Black thought she had asthma. It was an effort to walk up hills and stairs. Eventually, even vacuuming became difficult. But after an appointment with Dr. Denis O’Donnell at KGH, she learned she has Chronic Obstructive Pulmonary Disease (COPD), a condition that afflicts approximately 10% of Canadians. In its more advanced stages, COPD can significantly affect quality of life, as many patients are housebound and suffer from emotional anxiety.
“They avoid...Read more
Dr Damian Redfearn with patient Andrea Moore
Dr Redfearn is a cardiologist specialising in electrophysiology, the treatment of arrhythmia. His has particular expertise in catheter ablation of complex arrhythmia. He holds a doctorate degree in Medicine and is cross-appointed with the School of Computing and the Department of Biomedical and Molecular Sciences. He is the Director of the Heart Rhythm Service at Kingston General Hospital. Read more
Maternal Health Apps
An obstetrician at KGH has founded one of the first clinics to use pregnancy and the postpartum period to focus on disease prevention in women. Dr. Graeme Smith’s Maternal Health Clinic screens women for heart disease risk factors and provides resources and tools for maternal and family health. “Pregnancy is a stress test, in that it can reveal underlying health issues in the mother that may indicate an increased risk of future heart...Read more
Dr. Alberto Neder
Cardiovascular and respiratory diseases can have a devastating impact on a patient’s quality of life. But what if exercise could ease adverse symptoms and even help treat the illness? Clinician-scientist Dr. Alberto Neder has developed a unique lab that studies patients with both heart and lung disease, with the goal of better understanding how the various systems within the body work together under the stress of physical exercise. Exercise might seem like an odd...Read more
Dr. Damian Redfearn
Dr Redfearn is a cardiologist specialising in electrophysiology, the treatment of arrhythmia. His has particular expertise in catheter ablation of complex arrhythmia. He holds a doctorate degree in Medicine and is cross-appointed with the School of Computing and the Department of Biomedical and Molecular Sciences. He is the Director of the Heart Rhythm Service at Kingston General Hospital.
His research interests include catheter ablation and...Read more
Dr. David Berman
While cancer is often a serious and life-threatening disease, there are some slow growing cancers that may be better left untreated. Learning to distinguish between the two can save patients unnecessary surgery, chemotherapy or radiation treatments, as well as the risk of serious side-effects. Pathologist and researcher Dr. David Berman specializes in developing and improving existing diagnostic techniques to help doctors more accurately determine whether or not a cancer merits treatment, and if so, what...Read more
Dr. Denis O'Donnell
At first, Annetta Black thought she had asthma. It was an effort to walk up hills and stairs. Eventually, even vacuuming became difficult. But after an appointment with Dr. Denis O’Donnell at KGH, she learned she has Chronic Obstructive Pulmonary Disease (COPD), a condition that afflicts approximately 10% of Canadians
In its more advanced stages, COPD can significantly affect quality of life, as many patients are housebound and suffer from emotional anxiety. “They avoid...Read more
Dr. Gordon Boyd
No matter how brief, a critical illness can do longterm damage to the body and brain. Dr. Gordon Boyd, a neurologist, intensive care physician and clinician-scientist, is studying brain function, how it correlates with long-term neurological recovery, and how to improve outcomes for those who have suffered from cardiac arrest.
Dr. Boyd’s research is focused on predicting how patients react the first few days after a cardiac incident, and how to create tests...Read more
Dr. Graeme Smith
An obstetrician at KGH has founded one of the first clinics to use pregnancy and the postpartum period to focus on disease prevention in women. Dr. Graeme Smith’s Maternal Health Clinic screens women for heart disease risk factors and provides resources and tools for maternal and family health. “Pregnancy is a stress test, in that it can reveal underlying health issues in the mother that may indicate an increased risk of future heart...Read more
Dr. Stephen Scott
A game-changing technology invented at Queen’s University and used by scientists worldwide is having an exciting spinoff effect on hospital-based research – with potential benefits for patients around the globe. Read more
Dr. Stephen Archer
Pulmonary hypertension, high blood pressure in the lungs, is not just a chronic illness — it can also be fatal. Dr. Stephen Archer, the Head of Medicine at KGH and Queen’s University and a clinician scientist, is working to better understand how to treat and potentially cure pulmonary hypertension by delving deep inside the human body, examining cell structures to find abnormalities that can cause this disease.
Dr. Archer’s research in pulmonary hypertension revolves...Read more
Pulsepoint
You may have seen an Automatic External Defibrillator (AED) unit at your local hockey rink or public fitness centre — but do you know how to use it? Dr. Steven Brooks, a clinician-scientist in emergency medicine, is working to improve outcomes for cardiac arrest patients by researching how we can improve response and treatment, both in the community and in the hospital. While researching AEDs, Dr. Brooks discovered that it’s not a matter of...Read more
Dr. Stephen Vanner
Dr. Stephen Vanner, Director of the Gastrointestinal Research Unit (GIDRU), talks about his research in pain signalling in the gut in Irritable Bowel Syndrome and Inflammatory Bowel Disease, and how the multidisciplinary, collaborative approach of this research unit enables clinicians and basic scientists to translate their ideas into new approaches and treatments for these debilitating diseases. New funding has enabled GIDRU to develop a new...Read more
UHKF Video: Research at KGH
The University Hospitals Kingston Foundation (UHKF) is raising funds for creation of a Centre for Patient-Oriented Research at Kingston General Hospital. This facility will enable world-leading researchers to improve treatment and care in southeastern Ontario and beyond. This video, created for UHKF's Black Tie fundraiser, highlights leading-edge research at KGH. Read more
KGHRI Annual Report 2014
Year-end report of KGH Research Institute activities, 2013-2014 Read more
Dr. Jennifer Flemming
Breast and prostate cancer are often headline news – but liver cancer remains a largely hidden disease. According to the Canadian Liver Foundation, the death rate from liver illnesses has risen nearly 30% over the past eight years, and it’s estimated that one in 10 Canadians has some form of the disease. Dr. Jennifer Flemming, a clinician-scientist with training in Epidemiology and Biostatistics, is working to...Read more
Dr. Steven Brooks
You may have seen an Automatic External Defibrillator (AED) unit at your local hockey rink or public fitness centre — but do you know how to use it? Dr. Steven Brooks, a clinician-scientist in emergency medicine, is working to improve outcomes for cardiac arrest patients by researching how we can improve response and treatment, both in the community and in the hospital. While researching AEDs,...Read more
Dr. DJ Cook
Brain aneurysms can lead to a stroke, with devastating side effects that radically alter a patient’s quality of life. Dr. D.J. Cook, a cerebrovascular surgeon-scientist, is developing new treatments that minimize trauma related to brain aneurysm surgery, resulting in better outcomes, shorter hospital stays and an earlier return to normal life. He also runs a parallel research program to develop new treatments to enhance brain...Read more