Dr. Paula James, Clinician-Researcher, KGHRI

Paula James

MD
613-533-6329
Roles
Interests

Bleeding disorders, including hemophilia and von Willebrand disease. 

 

Dr. Paula James Let's Talk Period:

Dr. Paula James Hemophilia:

Bio

Dr. Paula James joined the Queen's Faculty of Health Sciences in 2004 and is a Clinician Scientist with 75% protected time for research.

A principal investigator in the Clinical and Molecular Hemostasis Research Group at Queen’s University, Dr. James has an active basic and clinical research program investigating the genetic basis of inherited bleeding disorders as well as the quantitation of bleeding symptoms.  Her group comprises post-doctoral fellows, graduate students, residents, medical students and research associates.  Recent research activities have included validating and publishing the Condensed MCMDM-1VWD Bleeding Questionnaire, which has gained international recognition, as well as optimizing a protocol for culturing BOEC (Blood Outgrowth Endothelial Cells) from patients with both inherited and acquired diseases, and the development of a self-administered bleeding assessment tool and a bleeding disorders website, Let’s Talk Period.

In addition to her research activities, Dr. James is the Medical Director of the Southeastern Ontario Inherited Bleeding Disorders Program and its aligned Women and Bleeding Disorders Clinic.  She was awarded “Researcher of the Year” by the National Hemophilia Foundation (US organization) in 2011, and the Mihran and Mary Basmajian Award for Excellence in Health Research by the Faculty of Health Sciences at Queen’s University in 2012.

 

Education and Honours

MD, University of Saskatchewan

2017 Cecil Harris Award – Canadian Hemophilia Society
2015 Inaugural Wallace H. Coulter Distinguished Lecture (Nominated) –International Society for Laboratory Hematology 
2014 Research Achievement Award – Queen's University Department of Medicine 
2012 Basmajian Award for Excellence in Health Sciences Research – Queen’s University 
2011 Researcher of the Year Award of Excellence – National Hemophilia Foundation 
2011 Clinician Scientist Development Program Award – Southeastern Ontario Medical Organization 
2008 Aesculapian Society Queen’s Medical School Phase IIA Teaching Award 
2008 CSL Behring Prof. Heimburger Award – Early Career Investigator Award 
2007 Excellence in Research Award, Department of Medicine Queen’s University 
2007 Bayer International Hemophilia Awards – Early Career Investigator Award 
2005 Young Investigator Award – International Society of Thrombosis and Hemostasis 
2003 John H. Crookston Award – Canadian Hematology Society 
2003 Aventis Behring – CHS – AHCDC Fellowship 
2002 Aventis Behring – CHS – AHCDC Fellowship
2000 Ian Holmes Senior Professionalism Award, University of Saskatchewan

 

Research

Research: 
Dr. James’s primary research interest is focused on von Willebrand disease and hemophilia. Projects not only examine the molecular genetic basis of these inherited bleeding disorders, but the impact of these disorders clinically as well. Her research also focuses on the quantitation of bleeding symptoms and understanding correlations between bleeding scores and the molecular basis of disease. Her program strives to achieve a "bench-to-bedside" perspective, translating our basic science research into clinically useful data. 

Other Publications

Website and self-administered Bleeding Assessment Tool (BAT): Let's Talk Period 
Heavy periods? You might have an undiagnosed bleeding disorder